Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | RRM2 | P31350 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291445 | 0.86 | KDM4E (0.34) | RAB9ANPC1KDM4ETRIM24TRIM33 | |
| SCHEMBL4728094 | 0.82 | RAB9A (0.36) | RAB9ANPC1KDM4ETRIM24TRIM33 | |
| SCHEMBL21284326 | 0.77 | KDM4E (0.36) | RAB9ANPC1KDM4ETRIM24TRIM33 | |
| SCHEMBL1376029 | 0.76 | TRIM24 (0.52) | RAB9ANPC1KDM4ETRIM24TRIM33 | |
| SCHEMBL31023942 | 0.76 | TRIM24 (0.52) | RAB9ANPC1KDM4ETRIM24TRIM33 | |
| SCHEMBL12521568 | 0.76 | KDM4E (0.39) | RAB9ANPC1KDM4ETRIM24TRIM33 | |
| SCHEMBL4725432 | 0.74 | EGFR (0.47) | RAB9ANPC1KDM4EL3MBTL1HTT | |
| SCHEMBL28029999 | 0.72 | AMY1A (0.49) | RAB9ANPC1KDM4ETRIM24TRIM33 | |
| SCHEMBL24137512 | 0.71 | ALDH1A1 (0.33) | RAB9ANPC1KDM4ETRIM24TRIM33 | |
| SCHEMBL14291612 | 0.71 | KDM4E (0.36) | KDM4EMAPTL3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008022467-A1 | 2-SUBSTITUTED AZAIN DOLES AND 2 SUBSTITUTED THIENOPYRROLES, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2008-02-28 | — | — | WO | disclosed |