Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.52 |
| ▸ | DRD2 | P14416 | 9/20 | 0.52 |
| ▸ | HTR2A | P28223 | 7/20 | 0.52 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729270 | 0.86 | DRD2 (0.71) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL4725919 | 0.85 | DRD2 (0.70) | HTR1ADRD2HTR2A | |
| SCHEMBL4729236 | 0.84 | DRD2 (0.52) | HTR1ADRD2HTR2AHTR1DHTR1B | |
| SCHEMBL4728870 | 0.84 | DRD2 (0.51) | HTR1ADRD2HTR2AHTR1DHTR1B | |
| SCHEMBL4728059 | 0.82 | DRD2 (0.75) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL4727283 | 0.79 | HTR1A (0.51) | HTR1ADRD2HTR2AHTR1BSLC6A4 | |
| SCHEMBL4727139 | 0.79 | DRD2 (0.47) | HTR1ADRD2HTR2AHTR1DHTR1B | |
| SCHEMBL4729394 | 0.77 | HTR1A (0.52) | HTR1ADRD2HTR2AHTR1DHTR1B | |
| SCHEMBL4727713 | 0.72 | DRD2 (0.72) | HTR1ADRD2HTR2ASLC6A4 | |
| SCHEMBL4728953 | 0.70 | DRD2 (0.70) | HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | claimed |