Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583301 | 0.94 | KMT2A (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK14 | |
| SCHEMBL4584119 | 0.93 | MAPK14 (0.44) | KMT2ASMN1; SMN2MAPK14RAB9APKM | |
| SCHEMBL4582502 | 0.89 | KMT2A (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK14 | |
| SCHEMBL4727782 | 0.87 | RAB9A (0.43) | KMT2AALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL4583084 | 0.87 | KMT2A (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4582586 | 0.86 | KMT2A (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK14 | |
| SCHEMBL4583868 | 0.86 | KMT2A (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4582544 | 0.86 | KMT2A (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4582792 | 0.85 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK14 | |
| SCHEMBL4583306 | 0.85 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |
| WO-2008028690-A1 | 1-(HET)ARYL-3-[HETARYL-PIPERIDIN-4-YL]-THIOUREAS AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |