Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.82 |
| ▸ | MAPT | P10636 | 9/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.82 |
| ▸ | HPGD | P15428 | 6/20 | 0.82 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.76 |
| ▸ | CASP1 | P29466 | 5/20 | 0.76 |
| ▸ | CASP7 | P55210 | 5/20 | 0.76 |
| ▸ | TP53 | P04637 | 8/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.75 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | DHFR | P00374 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31675772 | 0.91 | MEN1 (0.81) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| SCHEMBL345657 | 0.91 | MEN1 (1.00) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| SCHEMBL344155 | 0.91 | MEN1 (0.81) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| Fisetin SCHEMBL4887417 | 0.88 | MEN1 (0.81) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| 3,7-Dihydroxyflavone SCHEMBL2396684 | 0.87 | CYP3A4 (1.00) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| 3,7-Dihydroxyflavone SCHEMBL29625323 | 0.87 | CYP3A4 (1.00) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| Resokaempferol SCHEMBL30873045 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| Resokaempferol SCHEMBL344710 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| SCHEMBL345696 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP3A4KDM4EHSD17B10 | |
| Flavonol SCHEMBL27595696 | 0.85 | KDM4E (0.90) | MEN1KMT2ACYP3A4KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011538-A2 | METHODS OF USING FLAVONOIDS TO ENHANCE MEMORY | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2008-01-24 | — | — | WO | disclosed |