Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333004 | 0.79 | — | — | |
| SCHEMBL1521621 | 0.76 | — | — | |
| SCHEMBL7286316 | 0.69 | KMT2A (0.30) | — | |
| SCHEMBL1903501 | 0.68 | — | — | |
| SCHEMBL4346471 | 0.66 | NOS1 (0.31) | — | |
| SCHEMBL2646556 | 0.64 | — | — | |
| SCHEMBL335650 | 0.64 | APLNR (0.41) | APLNR | |
| SCHEMBL244348 | 0.62 | — | — | |
| SCHEMBL1649129 | 0.60 | CA1 (0.52) | CA1CA2APLNR | |
| SCHEMBL14462832 | 0.60 | CA1 (0.52) | CA1CA2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107690434-B | Fused tricyclic imidazopyrazine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-105829307-B | Tetrahydroimidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2020-07-24 | — | — | CN | disclosed |
| WO-2008020904-A2 | METHOD FOR REDUCING THE RISK OF OR PREVENTING INFECTION DUE TO SURGICAL OR INVASIVE MEDICAL PROCEDURES | RIB-X PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |