⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728213 | 0.79 | CA1 (0.38) | — | |
| SCHEMBL335650 | 0.66 | APLNR (0.41) | — | |
| SCHEMBL8263 | 0.60 | — | — | |
| SCHEMBL8099149 | 0.60 | APLNR (0.46) | — | |
| Hydrochloric Acid SCHEMBL19987689 | 0.58 | — | — | |
| Bromide SCHEMBL30609926 | 0.58 | — | — | |
| SCHEMBL9122745 | 0.58 | — | — | |
| SCHEMBL717087 | 0.57 | GABRA1 (0.56) | — | |
| SCHEMBL244348 | 0.56 | — | — | |
| SCHEMBL636980 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812026-A | Oral carbapenem compounds containing aminosulfonyl azetidinyl | SHANDONG XUANZHU PHARM TECH CO | 2012-12-05 | — | — | CN | disclosed |
| CN-102812026-A | Oral carbapenem compounds containing aminosulfonyl azetidinyl | SHANDONG XUANZHU PHARM TECH CO | 2012-12-05 | — | — | CN | disclosed |
| CN-102812026-A | Oral carbapenem compounds containing aminosulfonyl azetidinyl | SHANDONG XUANZHU PHARM TECH CO | 2012-12-05 | — | — | CN | disclosed |
| WO-2011097958-A1 | ORAL CARBAPENEM COMPOUNDS CONTAINING AMINOSULFONYL AZETIDINYL | 山东轩竹医药科技有限公司 (CN) | 2011-08-18 | — | — | WO | disclosed |