Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726861 | 0.93 | TEK (0.47) | RAF1BRAF | |
| SCHEMBL4729086 | 0.92 | CYP2C9 (0.47) | RAF1BRAF | |
| SCHEMBL4729370 | 0.92 | ABL1 (0.46) | RAF1BRAF | |
| SCHEMBL4781478 | 0.87 | RAF1 (0.47) | RAF1BRAF | |
| SCHEMBL4728277 | 0.86 | TEK (0.40) | RAF1BRAF | |
| SCHEMBL4729438 | 0.82 | MEN1 (0.54) | RAF1BRAF | |
| SCHEMBL4729210 | 0.82 | TRPV1 (0.42) | RAF1BRAF | |
| SCHEMBL4729212 | 0.81 | TRPV1 (0.41) | RAF1BRAF | |
| SCHEMBL4729484 | 0.81 | TRPV1 (0.41) | RAF1BRAF | |
| SCHEMBL4729516 | 0.81 | RAF1 (0.39) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |