Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.46 |
| ▸ | LCK | P06239 | 4/20 | 0.45 |
| ▸ | CSF1R | P07333 | 4/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 3/20 | 0.42 |
| ▸ | RAF1 | P04049 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726861 | 0.94 | TEK (0.47) | BRAFRAF1KDM4EALDH1A1MAPT | |
| SCHEMBL4729086 | 0.93 | CYP2C9 (0.47) | BRAFRAF1TEK | |
| SCHEMBL4728240 | 0.92 | RAF1 (0.49) | BRAFRAF1 | |
| SCHEMBL4728277 | 0.87 | TEK (0.40) | BRAFRAF1TEK | |
| SCHEMBL4729438 | 0.84 | MEN1 (0.54) | BRAFRAF1ALDH1A1MAPT | |
| SCHEMBL4729210 | 0.82 | TRPV1 (0.42) | MAPK14BRAFRAF1 | |
| SCHEMBL4729212 | 0.82 | TRPV1 (0.41) | MAPK14BRAFRAF1 | |
| SCHEMBL4729484 | 0.82 | TRPV1 (0.41) | MAPK14BRAFRAF1 | |
| SCHEMBL4729516 | 0.82 | RAF1 (0.39) | MAPK14BRAFRAF1 | |
| SCHEMBL4727399 | 0.81 | RAF1 (0.40) | MAPK14BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |