Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28233244 | 0.83 | CYP1A2 (0.41) | PPARGPPARAALDH1A1MAPT | |
| SCHEMBL4782527 | 0.81 | PPARG (0.35) | PPARGPPARACNR1CTSKMAOB | |
| SCHEMBL28815235 | 0.78 | KDM4E (0.54) | CTSKLMNAGAAMAPT | |
| SCHEMBL25179496 | 0.77 | MMP13 (0.46) | PPARGPPARACNR1FABP4FABP5 | |
| SCHEMBL25270118 | 0.77 | MMP13 (0.46) | PPARGPPARACNR1FABP4FABP5 | |
| SCHEMBL22804109 | 0.75 | SLC7A5 (0.42) | CTSK | |
| SCHEMBL7385110 | 0.75 | CYP2C19 (0.49) | CTSKALDH1A1 | |
| SCHEMBL7106924 | 0.74 | ITGB1 (0.34) | PPARANPC1 | |
| SCHEMBL22804107 | 0.74 | L3MBTL1 (0.52) | ALDH1A1MAPT | |
| SCHEMBL27865011 | 0.72 | P4HTM (0.44) | PPARGPPARAMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008036308-A2 | AMINO-SUBSTITUTED HETEROCYCLES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC (US) | 2008-03-27 | — | — | WO | disclosed |