SCHEMBL22804109

SCHEMBL22804109

CC(C)(C)ON(C=O)[C@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.42
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
OPRK1 P41145 3/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
OPRM1 P35372 6/20 0.37
OPRD1 P41143 2/20 0.37
BLM P54132 1/20 0.37
FOLH1 Q04609 1/20 0.36
MIF P14174 1/20 0.36
TAAR1 Q96RJ0 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28233244 0.89 CYP1A2 (0.41) SLC7A5OPRK1OPRM1OPRD1FOLH1
SCHEMBL7106924 0.88 ITGB1 (0.34) SLC7A5
SCHEMBL7299550 0.84 PPARA (0.40)
SCHEMBL7299078 0.81 PPARD (0.39)
SCHEMBL7424094 0.81 ITGB3 (0.41)
SCHEMBL7292750 0.80 ITGB3 (0.42) OPRK1OPRM1OPRD1
SCHEMBL7417141 0.78 SLC7A5 (0.42) SLC7A5OPRK1OPRM1OPRD1MIF
SCHEMBL9308843 0.78 ITGB3 (0.58)
SCHEMBL27507556 0.77 ATM (0.41) MIF
SCHEMBL8182265 0.77 SRR (0.43) CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO disclosed