SCHEMBL4728441

SCHEMBL4728441

N[C@@H](CC(=O)O)C(=O)OC(=O)N1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.38
DPP7 Q9UHL4 3/20 0.35
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.32
KCNH2 Q12809 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ATM Q13315 1/20 0.31
NPC1 O15118 1/20 0.30
GAA P10253 2/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728435 0.86 ALDH1A1 (0.33) DPP7ALDH1A1POLBSMN1; SMN2ATM
SCHEMBL1653844 0.77 SLC22A6 (0.39) DPP4SMN1; SMN2LMNA
SCHEMBL30357425 0.76 DPP4 (0.50) DPP4DPP7
SCHEMBL18263746 0.75 DPP4 (0.40) DPP4DPP7ALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL11804611 0.75 SLC22A6 (0.38) DPP4SMN1; SMN2LMNA
SCHEMBL16310466 0.74 DPP4 (0.49) DPP4DPP7HTT
SCHEMBL3346333 0.74 DPP4 (0.49) DPP4DPP7HTT
SCHEMBL21315720 0.71 TDP1 (0.39) DPP4KMT2ASMN1; SMN2LMNA
SCHEMBL214692 0.71 TDP1 (0.39) DPP4KMT2ASMN1; SMN2LMNA
SCHEMBL28002998 0.71 SLC22A6 (0.38) SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124693-B2 Hydroxyalkylurethane kinetic hydrate inhibitors INDORAMA VENTURES OXIDES LLC (US) 2021-09-21 US disclosed
EP-3452532-B1 SUCCINIMIDE-BASED COPOLYMERS AND USE AS HYDRATE INHIBITORS SAUDI ARABIAN OIL CO (SA) 2021-03-24 EP disclosed
WO-2018160306-A1 HYDROXYALKYLURETHANE KINETIC HYDRATE INHIBITORS HUNTSMAN PETROCHEMICAL LLC (US) 2018-09-07 WO disclosed
US-9303201-B2 Method of inhibiting the formation of gas hydrates using amidines and guanidines ECO INHIBITORS AS (NO) 2016-04-05 US disclosed
US-20140256599-A1 METHOD OF INHIBITING THE FORMATION OF GAS HYDRATES USING AMIDINES AND GUANIDINES ECO INHIBITORS AS (NO) 2014-09-11 US disclosed
WO-2013053770-A1 METHOD OF INHIBITING THE FORMATION OF GAS HYDRATES USING AMINE OXIDES ECO INHIBITORS AS (NO) 2013-04-18 WO disclosed
WO-2013053766-A1 METHOD OF INHIBITING THE FORMATION OF GAS HYDRATES USING AMIDINES AND GUANIDINES ECO INHIBITORS AS (NO) 2013-04-18 WO disclosed
WO-2008023989-A1 ADDITIVES FOR INHIBITING GAS HYDRATE FORMATION UNIVERSITETET I STAVANGER (NO) 2008-02-28 WO disclosed
EP-0828778-B1 CLATHRATE HYDRATE INHIBITOR AND METHOD OF INHIBITING THE FORMATION OF CLATHRATE HYDRATES USING IT NIPPON CATALYTIC CHEM IND (JP) 2004-05-12 EP disclosed
US-6319971-B1 CONTROLLING GAS HYDRATE FORMATION, ESPECIALLY IN PIPES AND OIL AND GAS WELLS BY USING A POLYMER MIXTURE THAT PREVENTS HYDRATE NUCLEATION; ONE POLYMER'S WEIGHT BOLTZMANN FACTOR IS HIGHER THAN THE OTHER RF-PROCOM A/S (NO) 2001-11-20 US disclosed
US-6232273-B1 MACROMOLECULAR COMPOUND WITH NITROGEN-CONTAINING RING PENDANT TO THE POLYMER CHAIN, SUCH AS POLYMER OF (METH)ACRYLOYL PYRROLIDINE, PYRROLIDINOCARBONYLETHYL (METH)ACRYLATE, 2-OXO-PYRROLIDINO-ETHYL (METH)ACRYLATE, ETC. NIPPON SHOKUBAI CO., LTD. (JP) 2001-05-15 US disclosed
WO-1998053007-A1 COMPOSITION FOR CONTROLLING CLATHRATE HYDRATES AND A METHOD FOR CONTROLLING CLATHRATE HYDRATE FORMATION RF-PROCOM A/S (NO) 1998-11-26 WO disclosed
EP-0828778-A1 CLATHRATE HYDRATE INHIBITOR AND METHOD OF INHIBITING THE FORMATION OF CLATHRATE HYDRATES USING IT NIPPON SHOKUBAI CO., LTD. (JP) 1998-03-18 EP disclosed
WO-1996038492-A1 CLATHRATE HYDRATE INHIBITOR AND METHOD OF INHIBITING THE FORMATION OF CLATHRATE HYDRATES USING IT NIPPON SHOKUBAI CO., LTD. (JP) 1996-12-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256599-A1 METHOD OF INHIBITING THE FORMATION OF GAS HYDRATES USING AMIDINES AND GUANIDINES MAGI3, GEMIN5, GCG DPP4 1671/4885DPP7 2240/4885ALDH1A1 3524/4885
US-11124693-B2 Hydroxyalkylurethane kinetic hydrate inhibitors HDHD5, UNG, OGG1 DPP4 4185/4885DPP7 3977/4885ALDH1A1 462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.