Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 4/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784365 | 0.86 | CDK8 (0.38) | CDK8PPARAMAPK14MAPK12MAPK13 | |
| SCHEMBL4728555 | 0.82 | PPARA (0.41) | CDK8PPARAMAPK14MAPK12MAPK13 | |
| SCHEMBL4726243 | 0.76 | PPARA (0.38) | PPARAPPARD | |
| SCHEMBL4728593 | 0.75 | PPARA (0.48) | PPARAPPARD | |
| SCHEMBL4731241 | 0.74 | PPARG (0.49) | PPARAPPARD | |
| SCHEMBL4729759 | 0.73 | PPARA (0.41) | PPARAPPARD | |
| SCHEMBL4728913 | 0.72 | PPARA (0.51) | PPARAPPARD | |
| SCHEMBL4728611 | 0.71 | HDAC6 (0.40) | PPARA | |
| SCHEMBL4730644 | 0.70 | PPARG (0.53) | PPARAPPARD | |
| SCHEMBL4726355 | 0.69 | PPARD (0.66) | PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |