SCHEMBL472876

SCHEMBL472876

CC(C)(C)C(=O)OC[C@H]1O[C@@H](OCc2ccccc2)[C@H](OC(=O)CCl)[C@@H](OC(=O)C(C)(C)C)[C@@H]1F

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 2/20 0.37
▸ FGF2 P09038 2/20 0.37
▸ VEGFA P15692 2/20 0.37
▸ HPSE Q9Y251 2/20 0.37
▸ LGALS8 O00214 1/20 0.37
▸ NT5E P21589 1/20 0.37
▸ LMNA P02545 2/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ PTPN1 P18031 5/20 0.34
▸ CDC25B P30305 5/20 0.34
▸ PTPN2 P17706 2/20 0.33
▸ PTPN6 P29350 2/20 0.33
▸ PTPN11 Q06124 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472853 0.90 NT5E (0.44) FGF1FGF2VEGFAHPSENT5E
SCHEMBL2629589 0.90 LGALS8 (0.43) FGF1FGF2VEGFAHPSELGALS8
SCHEMBL472845 0.90 LGALS8 (0.43) FGF1FGF2VEGFAHPSELGALS8
SCHEMBL14075623 0.90 LGALS8 (0.43) FGF1FGF2VEGFAHPSELGALS8
SCHEMBL14075626 0.85 LGALS8 (0.42) FGF1FGF2VEGFAHPSELGALS8
SCHEMBL472852 0.85 LGALS8 (0.42) FGF1FGF2VEGFAHPSELGALS8
SCHEMBL2629582 0.85 LGALS8 (0.42) FGF1FGF2VEGFAHPSELGALS8
SCHEMBL10077887 0.84 LGALS8 (0.41) FGF1FGF2VEGFAHPSELGALS8
SCHEMBL14075624 0.81 CYP2D6 (0.36) LMNACYP2D6
SCHEMBL2629586 0.81 CYP2D6 (0.36) LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412720-B1 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides GLYTECH INC (JP) 2015-10-21 — — EP disclosed
EP-1520858-B1 Process for preparing glycopeptides having asparagine-linked oligosaccharides GLYTECH INC (JP) 2013-11-27 — — EP disclosed
US-8399656-B2 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides OTSUKA CHEMICAL CO., LTD. (JP) 2013-03-19 — — US disclosed
US-20120035345-A1 PROCESS FOR PREPARING GLYCOPEPTIDES HAVING ASPARAGINE-LINKED OLIGOSACCHARIDES, AND THE GLYCOPEPTIDES OTSUKA CHEMICAL CO., LTD. (JP) 2012-02-09 — — US disclosed
EP-2412720-A2 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides Otsuka Chemical Co., Ltd. (JP) 2012-02-01 — — EP disclosed
US-8063202-B2 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides OTSUKA CHEMICAL CO., LTD. (JP) 2011-11-22 — — US disclosed
US-7943763-B2 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides OTSUKA CHEMICAL HOLDINGS CO., LTD. (JP) 2011-05-17 — — US disclosed
US-20090234095-A1 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides GLYTECH, INC. (JP) 2009-09-17 — — US disclosed
US-20050222382-A1 Process for producing sugar peptide having asparagine sugar chain and the sugar peptide GLYTECH, INC. (JP) 2005-10-06 — — US disclosed
EP-1520858-A1 PROCESS FOR PRODUCING SUGAR PEPTIDE HAVING ASPARAGINE SUGAR CHAIN AND THE SUGAR PEPTIDE OTSUKA CHEMICAL COMPANY, LTD. (JP) 2005-04-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035345-A1 PROCESS FOR PREPARING GLYCOPEPTIDES HAVING ASPARAGINE-LINKED OLIGOSACCHARIDES, AND THE GLYCOPEPTIDES ASNS, BSG, ANPEP FGF1 2220/4885FGF2 1772/4885VEGFA 1323/4885
US-20050222382-A1 Process for producing sugar peptide having asparagine sugar chain and the sugar peptide ASNS, ANPEP, GCG FGF1 1803/4885FGF2 1511/4885VEGFA 979/4885
US-20090234095-A1 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides ASNS, ANPEP, B3GNT2 FGF1 2412/4885FGF2 2059/4885VEGFA 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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