SCHEMBL10077887

SCHEMBL10077887

C[C@@H]1C(OC(=O)CCl)[C@H](OCc2ccccc2)OC(COC(=O)C(C)(C)C)[C@@H]1O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 1/20 0.41
▸ FGF1 P05230 2/20 0.38
▸ FGF2 P09038 2/20 0.38
▸ VEGFA P15692 2/20 0.38
▸ HPSE Q9Y251 2/20 0.38
▸ SSTR5 P35346 3/20 0.36
▸ NT5E P21589 1/20 0.35
▸ LMNA P02545 2/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ TACR1 P25103 1/20 0.34
▸ PRKCA P17252 1/20 0.34
▸ PRKCD Q05655 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ SSTR3 P32745 2/20 0.34
▸ MCHR1 Q99705 2/20 0.34
▸ PTPN1 P18031 1/20 0.34
▸ CDC25B P30305 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472845 0.91 LGALS8 (0.43) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL14075623 0.91 LGALS8 (0.43) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL2629589 0.91 LGALS8 (0.43) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL10077913 0.85 LGALS8 (0.39) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL472876 0.84 FGF1 (0.37) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL14683528 0.82 FGF1 (0.43) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL2629592 0.81 LGALS8 (0.48) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL14075622 0.81 LGALS8 (0.48) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL14409788 0.81 LGALS8 (0.48) LGALS8FGF1FGF2VEGFAHPSE
SCHEMBL6552374 0.81 TACR2 (0.43) LGALS8FGF1FGF2VEGFAHPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399656-B2 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides OTSUKA CHEMICAL CO., LTD. (JP) 2013-03-19 — — US disclosed
US-20120035345-A1 PROCESS FOR PREPARING GLYCOPEPTIDES HAVING ASPARAGINE-LINKED OLIGOSACCHARIDES, AND THE GLYCOPEPTIDES OTSUKA CHEMICAL CO., LTD. (JP) 2012-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035345-A1 PROCESS FOR PREPARING GLYCOPEPTIDES HAVING ASPARAGINE-LINKED OLIGOSACCHARIDES, AND THE GLYCOPEPTIDES ASNS, BSG, ANPEP LGALS8 132/4885FGF1 2220/4885FGF2 1772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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