SCHEMBL472853

SCHEMBL472853

CC(C)(C)C(=O)OC[C@H]1O[C@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@@H](OC(=O)C(C)(C)C)[C@@H]1F

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.44
▸ PTPN1 P18031 7/20 0.40
▸ CDC25B P30305 7/20 0.40
▸ PTPN2 P17706 4/20 0.39
▸ PTPN6 P29350 4/20 0.39
▸ PTPN11 Q06124 4/20 0.39
▸ FGF1 P05230 2/20 0.38
▸ FGF2 P09038 2/20 0.38
▸ VEGFA P15692 2/20 0.38
▸ HPSE Q9Y251 2/20 0.38
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA9 Q16790 1/20 0.37
▸ SSTR1 P30872 1/20 0.37
▸ SSTR2 P30874 1/20 0.37
▸ SSTR4 P31391 1/20 0.37
▸ SSTR3 P32745 1/20 0.37
▸ SSTR5 P35346 1/20 0.37
▸ POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14075626 0.91 LGALS8 (0.42) NT5EPTPN1CDC25BFGF1FGF2
SCHEMBL472852 0.91 LGALS8 (0.42) NT5EPTPN1CDC25BFGF1FGF2
SCHEMBL2629582 0.91 LGALS8 (0.42) NT5EPTPN1CDC25BFGF1FGF2
SCHEMBL14409790 0.90 NT5E (0.51) NT5EPTPN1CDC25BPTPN2PTPN6
SCHEMBL472876 0.90 FGF1 (0.37) NT5EPTPN1CDC25BPTPN2PTPN6
SCHEMBL6552379 0.87 PTPN1 (0.50) NT5EPTPN1CDC25BPTPN2PTPN6
SCHEMBL13695054 0.85 NT5E (0.36) NT5EFGF1FGF2VEGFAHPSE
SCHEMBL14075625 0.85 NT5E (0.36) NT5EFGF1FGF2VEGFAHPSE
SCHEMBL2629592 0.83 LGALS8 (0.48) NT5EPTPN1CDC25BFGF1FGF2
SCHEMBL14409788 0.83 LGALS8 (0.48) NT5EPTPN1CDC25BFGF1FGF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412720-B1 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides GLYTECH INC (JP) 2015-10-21 — — EP disclosed
EP-1520858-B1 Process for preparing glycopeptides having asparagine-linked oligosaccharides GLYTECH INC (JP) 2013-11-27 — — EP disclosed
US-8399656-B2 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides OTSUKA CHEMICAL CO., LTD. (JP) 2013-03-19 — — US disclosed
US-20120035345-A1 PROCESS FOR PREPARING GLYCOPEPTIDES HAVING ASPARAGINE-LINKED OLIGOSACCHARIDES, AND THE GLYCOPEPTIDES OTSUKA CHEMICAL CO., LTD. (JP) 2012-02-09 — — US disclosed
EP-2412720-A2 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides Otsuka Chemical Co., Ltd. (JP) 2012-02-01 — — EP disclosed
US-8063202-B2 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides OTSUKA CHEMICAL CO., LTD. (JP) 2011-11-22 — — US disclosed
US-20090234095-A1 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides GLYTECH, INC. (JP) 2009-09-17 — — US disclosed
EP-1520858-A1 PROCESS FOR PRODUCING SUGAR PEPTIDE HAVING ASPARAGINE SUGAR CHAIN AND THE SUGAR PEPTIDE OTSUKA CHEMICAL COMPANY, LTD. (JP) 2005-04-06 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035345-A1 PROCESS FOR PREPARING GLYCOPEPTIDES HAVING ASPARAGINE-LINKED OLIGOSACCHARIDES, AND THE GLYCOPEPTIDES ASNS, BSG, ANPEP NT5E 285/4885PTPN1 2272/4885CDC25B 4781/4885
US-20090234095-A1 Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides ASNS, ANPEP, B3GNT2 NT5E 325/4885PTPN1 2323/4885CDC25B 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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