Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611109 | 0.92 | AOC3 (0.40) | AOC3C5AR1ALDH1A1ABCB1TSHR | |
| SCHEMBL7610365 | 0.92 | AOC3 (0.40) | AOC3C5AR1ALDH1A1ABCB1TSHR | |
| SCHEMBL7610616 | 0.87 | ALDH1A1 (0.43) | AOC3C5AR1TRPM8ALDH1A1ABCB1 | |
| SCHEMBL4728111 | 0.85 | KMT2A (0.43) | ALDH1A1ABCB1NPC1POLBMEN1 | |
| SCHEMBL7608227 | 0.85 | PTGS1 (0.40) | ALOX5BCHEEPORMAPTRAB9A | |
| SCHEMBL7611069 | 0.83 | MEN1 (0.37) | TRPM8ALDH1A1BCHENPC1POLB | |
| SCHEMBL7606237 | 0.80 | NPC1 (0.39) | ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL7608457 | 0.80 | BCHE (0.41) | ALOX5BCHEEPORMAPTRAB9A | |
| SCHEMBL7606579 | 0.80 | NR1H3 (0.43) | AOC3C5AR1ALDH1A1ALOX5TSHR | |
| SCHEMBL719264 | 0.79 | ALDH1A1 (0.41) | AOC3TRPM8ALDH1A1ABCB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035380-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF HIGH PURITY FORMOTEROL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | NATCO PHARMA LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |