Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606168 | 0.91 | PTPN2 (0.41) | NR1H3HTTALDH1A1MAPTLRRK2 | |
| SCHEMBL7605972 | 0.88 | ALDH1A1 (0.44) | NR1H3LMNAHTTALDH1A1MAPT | |
| SCHEMBL7611109 | 0.87 | AOC3 (0.40) | NR1H3ALDH1A1MAPTC5AR1TSHR | |
| SCHEMBL7610365 | 0.87 | AOC3 (0.40) | NR1H3ALDH1A1MAPTC5AR1TSHR | |
| SCHEMBL7611191 | 0.84 | ALDH1A1 (0.44) | NR1H3ALDH1A1MAPTC5AR1LRRK2 | |
| SCHEMBL7606574 | 0.83 | NR1H3 (0.49) | NR1H3LMNAHTTALDH1A1MAPT | |
| SCHEMBL7605885 | 0.82 | MAPT (0.45) | LMNAHTTALDH1A1MAPTLRRK2 | |
| SCHEMBL7608227 | 0.80 | PTGS1 (0.40) | LMNAMAPTALOX5RAB9ASMN1; SMN2 | |
| SCHEMBL7610616 | 0.78 | ALDH1A1 (0.43) | NR1H3LMNAHTTALDH1A1MAPT | |
| SCHEMBL4728111 | 0.77 | KMT2A (0.43) | LMNAHTTALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |