Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.38 |
| ▸ | CETP | P11597 | 13/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729901 | 0.89 | CETP (0.38) | CCR2CETPTACR1 | |
| SCHEMBL4730989 | 0.88 | CETP (0.38) | CCR2CETPTACR1 | |
| SCHEMBL4728683 | 0.86 | KDM4E (0.40) | CETPTACR1 | |
| SCHEMBL4728130 | 0.86 | CETP (0.40) | CETPTACR1 | |
| SCHEMBL4782018 | 0.84 | CETP (0.39) | CETPTACR1 | |
| SCHEMBL4731791 | 0.84 | CETP (0.40) | CETPTACR1 | |
| SCHEMBL4729719 | 0.84 | CCR2 (0.37) | CCR2CETPTACR1 | |
| SCHEMBL4732027 | 0.83 | TACR1 (0.38) | TACR1 | |
| SCHEMBL4729348 | 0.83 | CETP (0.38) | CCR2CETPTACR1 | |
| SCHEMBL4732208 | 0.82 | CCR2 (0.36) | CCR2CETPTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |