Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 15/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732423 | 0.96 | CETP (0.41) | CETPTMEM97KCNH2TACR1 | |
| SCHEMBL4728130 | 0.90 | CETP (0.40) | CETPTMEM97KCNH2TACR1 | |
| SCHEMBL4728785 | 0.89 | TMEM97 (0.41) | CETPTMEM97KCNH2TACR1 | |
| SCHEMBL4731680 | 0.89 | CETP (0.43) | CETPTACR1 | |
| SCHEMBL4731307 | 0.89 | CETP (0.44) | CETPTACR1 | |
| SCHEMBL4782018 | 0.88 | CETP (0.39) | CETPTMEM97KCNH2TACR1 | |
| SCHEMBL4728797 | 0.84 | CCR2 (0.38) | CETPTACR1 | |
| SCHEMBL4729901 | 0.84 | CETP (0.38) | CETPTACR1 | |
| SCHEMBL4729348 | 0.83 | CETP (0.38) | CETPTACR1 | |
| SCHEMBL4730989 | 0.81 | CETP (0.38) | CETPTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |