Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 5/20 | 0.67 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MGLL | Q99685 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | GRM5 | P41594 | 1/20 | 0.60 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30758624 | 1.00 | NR1H3 (0.67) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL12231557 | 0.90 | MEN1 (0.61) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL13084672 | 0.88 | MGLL (0.62) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL12639229 | 0.87 | MGLL (0.57) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL11615606 | 0.85 | NR1H3 (0.61) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL17326658 | 0.84 | MGLL (0.54) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL14731789 | 0.84 | MEN1 (0.61) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL10013240 | 0.83 | ALDH1A1 (0.65) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL725608 | 0.82 | NR1H3 (0.67) | NR1H3NR1H2MEN1KMT2AALDH1A1 | |
| SCHEMBL5658435 | 0.82 | ALDH1A1 (0.63) | NR1H3NR1H2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466799-A | Preparation method of N-substituted phthalimide compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-110330526-B | Green synthesis method of thiophosphite | 成都理工大学 | 2021-11-26 | — | — | CN | disclosed |
| WO-2008029168-A2 | TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | SUMMIT CORPORATION PLC (GB) | 2008-03-13 | — | — | WO | disclosed |
| EP-0384895-B1 | 2- Or 3-fluorane-dicarboxylic imides, process for their preparation and their use in recording materials | CIBA GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |
| US-5066814-A | 2-DICARBOXIMIDEFLUORANE OR 3-DICARBOXIMIDEFLUORANE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0384895-A2 | 2- Or 3-fluorane-dicarboxylic imides, process for their preparation and their use in recording materials | CIBA-GEIGY AG (CH) | 1990-08-29 | — | — | EP | disclosed |