SCHEMBL4728840

SCHEMBL4728840

CCN(C(=O)O)[C@@H](CCCCN)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.46
RNPEP Q9H4A4 1/20 0.44
CPB2 Q96IY4 7/20 0.42
EPOR P19235 1/20 0.37
FOLH1 Q04609 1/20 0.36
GABRR1 P24046 2/20 0.35
GRIK1 P39086 2/20 0.35
GRIK2 Q13002 2/20 0.35
SLC1A2 P43004 1/20 0.35
SLC1A1 P43005 1/20 0.35
GNAI3 P08754 1/20 0.34
GNAO1 P09471 1/20 0.34
GNAI1 P63096 1/20 0.34
SLC6A5 Q9Y345 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL787391 1.00 GSR (0.46) GSRRNPEPCPB2EPORFOLH1
SCHEMBL29067246 0.83 GRIK1 (0.41) GSRRNPEPCPB2GRIK1GRIK2
SCHEMBL4298060 0.81 GSR (0.48) GSRRNPEPCPB2EPORFOLH1
SCHEMBL4298056 0.81 GSR (0.48) GSRRNPEPCPB2EPORFOLH1
SCHEMBL11013496 0.81 SLC6A5 (0.43) GSRRNPEPCPB2GRIK1GRIK2
SCHEMBL28509039 0.80 GSR (0.47) GSRRNPEPCPB2FOLH1GABRR1
SCHEMBL6267879 0.80 GSR (0.47) GSRRNPEPCPB2FOLH1GABRR1
SCHEMBL2725758 0.78 GSR (0.48) GSRRNPEPCPB2EPORFOLH1
SCHEMBL634033 0.78 GSR (0.48) GSRRNPEPCPB2EPORFOLH1
SCHEMBL6739029 0.77 CPB2 (0.45) GSRRNPEPCPB2FOLH1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025560-A1 METHOD FOR THE REVIVAL OF MICROGLIA AND ASTROCYTES AND APPLICATIONS THEREOF UNIVERSITY OF SOUTH CAROLINA 2025-01-23 US claimed
US-20250025560-A1 METHOD FOR THE REVIVAL OF MICROGLIA AND ASTROCYTES AND APPLICATIONS THEREOF UNIVERSITY OF SOUTH CAROLINA 2025-01-23 US disclosed
CN-114847317-B Method for simultaneously reducing the content of 4-methylimidazole and advanced glycation end products in bakery products based on natural active ingredients 江南大学 2023-08-11 CN disclosed
CN-114847317-A Method for simultaneously reducing the content of 4-methylimidazole and advanced glycation end products in bakery products based on natural active ingredients 江南大学 2022-08-05 CN disclosed
WO-2008029162-A1 BIOMARKERS THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2008-03-13 WO disclosed
EP-1272843-B1 METHOD FOR IDENTIFYING REGULATORS OF PROTEIN-AGE FORMATION NIADYNE CORP (US) 2007-06-20 EP disclosed
US-6716635-B2 MIXING A SUBSTANCE TO BE TESTED, A HISTONE H1 AND ADP-RIBOSE AND MEASURING THE FLUORESCENCE AND PROTEIN CROSSLINKING; COMBINATORIAL LIBRARIES; ANTIDIABETIC AGENTS; ATHEROSCLEROSIS, CHRONIC NEURODEGENERATIVE DISEASES, E.G.,ALZHEIMER'S; UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2004-04-06 US disclosed
WO-2003020899-A2 COMPOSITIONS AND METHODS RELATING TO LUNG SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2003-03-13 WO disclosed
EP-1272843-A2 METHOD FOR IDENTIFYING REGULATORS OF PROTEIN-AGE FORMATION Niadyne Corporation (US) 2003-01-08 EP disclosed
US-20020037496-A1 Method for identifying regulators of protein-advanced glycation end product (protein-AGE) formation NIADYNE, INC. 2002-03-28 US disclosed
WO-2001079842-A2 METHOD FOR IDENTIFYING REGULATORS OF PROTEIN-AGE FORMATION NIADYNE CORPORATION (US) 2001-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250025560-A1 METHOD FOR THE REVIVAL OF MICROGLIA AND ASTROCYTES AND APPLICATIONS THEREOF L1CAM, CD274, PDCD1LG2 GSR 592/4885RNPEP 1788/4885CPB2 4722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.