Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.57 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14292119 | 0.83 | ALDH1A1 (0.56) | CNR2ALDH1A1HPGD | |
| SCHEMBL4727961 | 0.83 | DRD3 (0.69) | CNR2HTR7DRD3ABCB1MEN1 | |
| SCHEMBL28007695 | 0.82 | CNR2 (0.60) | CNR2ALDH1A1HPGD | |
| SCHEMBL17444689 | 0.82 | CNR2 (0.61) | CNR2MEN1KMT2ASIGMAR1 | |
| SCHEMBL4729412 | 0.82 | SIGMAR1 (0.72) | CNR2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL4727196 | 0.81 | CNR2 (0.57) | CNR2ALDH1A1HPGD | |
| SCHEMBL13305298 | 0.80 | DRD3 (0.65) | CNR2HTR7DRD3ABCB1TMEM97 | |
| SCHEMBL28007691 | 0.80 | CNR2 (0.64) | CNR2 | |
| SCHEMBL28007398 | 0.80 | CNR2 (0.64) | CNR2 | |
| SCHEMBL17444718 | 0.79 | CNR2 (0.57) | CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |