Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CALML3 | P27482 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261619 | 1.00 | PKM (0.56) | PKMCALML3POLBCYP2C19CYP2C9 | |
| SCHEMBL4728524 | 0.82 | CNR1 (0.46) | CALML3POLBMAOAMAOBF10 | |
| SCHEMBL14261644 | 0.79 | CALML3 (0.52) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL14261417 | 0.79 | CALML3 (0.52) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL14261606 | 0.77 | F10 (0.47) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL4728137 | 0.75 | CALML3 (0.45) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL4783498 | 0.73 | KDM4E (0.49) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL14261404 | 0.73 | KDM4E (0.49) | CALML3CYP2C19CYP2C9MAOAMAOB | |
| SCHEMBL10151464 | 0.73 | MAOA (0.45) | CALML3MAOAMAOBF10 | |
| SCHEMBL14261333 | 0.73 | DDB1 (0.49) | MAOAMAOBF10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | claimed |
| WO-2008029266-A1 | STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-03-13 | — | — | WO | disclosed |