Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.79 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.79 |
| ▸ | TNKS | O95271 | 1/20 | 0.79 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.79 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.79 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.79 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.79 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.79 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.79 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.79 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.58 |
| ▸ | TERT | O14746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pj34 SCHEMBL422317 | 0.88 | PARP1 (1.00) | PARP1PARP14TNKSPARP15PARP10 | |
| Pj34 SCHEMBL29355630 | 0.88 | PARP1 (1.00) | PARP1PARP14TNKSPARP15PARP10 | |
| Pj34 SCHEMBL29375455 | 0.88 | PARP1 (1.00) | PARP1PARP14TNKSPARP15PARP10 | |
| Pj34 SCHEMBL29419962 | 0.87 | PARP1 (0.98) | PARP1PARP14TNKSPARP15PARP10 | |
| Pj34 SCHEMBL5074001 | 0.87 | PARP1 (0.98) | PARP1PARP14TNKSPARP15PARP10 | |
| Pj34 SCHEMBL29478302 | 0.87 | PARP1 (0.98) | PARP1PARP14TNKSPARP15PARP10 | |
| Pj34 SCHEMBL31153313 | 0.86 | TRPM2 (1.00) | PARP1PARP14TNKSPARP15PARP10 | |
| SCHEMBL19308466 | 0.83 | P2RY12 (0.71) | PARP1PARP14TNKSPARP15PARP10 | |
| SCHEMBL19308451 | 0.83 | KDM4E (0.74) | PARP1PARP14TNKSPARP15PARP10 | |
| SCHEMBL31488126 | 0.80 | MTNR1A (1.00) | KDM4EMTNR1AMTNR1BKMT2AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |