Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4727017 | 0.99 | GRM1 (0.50) | GRM1SLC6A4MAPK1MGAMKDM4E | |
| SCHEMBL8215059 | 0.86 | GRM1 (0.40) | GRM1SLC6A4MGAMNPC1RAB9A | |
| SCHEMBL4728861 | 0.82 | HPGDS (0.46) | GRM1 | |
| SCHEMBL4729426 | 0.82 | ALDH1A1 (0.49) | GRM1NPC1RAB9AALDH1A1 | |
| SCHEMBL2135499 | 0.80 | SLC6A4 (0.52) | SLC6A4MGAMLMNARAB9ASMN1; SMN2 | |
| SCHEMBL10288441 | 0.80 | SLC6A4 (0.52) | SLC6A4MGAMLMNARAB9ASMN1; SMN2 | |
| SCHEMBL2135495 | 0.80 | SLC6A4 (0.52) | SLC6A4MGAMLMNARAB9ASMN1; SMN2 | |
| SCHEMBL4731779 | 0.80 | GRM1 (0.51) | GRM1MAPK1KDM4EMAPTNPC1 | |
| SCHEMBL4727005 | 0.80 | GRM1 (0.48) | GRM1MAPK1KDM4EMAPTLMNA | |
| SCHEMBL4729407 | 0.79 | PDGFRB (0.48) | GRM1KDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |