Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 12/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213684 | 0.87 | PDGFRB (0.46) | PDGFRBPDGFRAGRM1 | |
| SCHEMBL4728861 | 0.85 | HPGDS (0.46) | GRM1 | |
| SCHEMBL4729426 | 0.85 | ALDH1A1 (0.49) | PDGFRBPDGFRAGRM1MEN1KMT2A | |
| SCHEMBL4727005 | 0.81 | GRM1 (0.48) | PDGFRBPDGFRAGRM1MEN1KMT2A | |
| SCHEMBL4731779 | 0.81 | GRM1 (0.51) | GRM1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4728893 | 0.79 | GRM1 (0.51) | GRM1KDM4EALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL4727017 | 0.78 | GRM1 (0.50) | GRM1KDM4EALDH1A1HTT | |
| SCHEMBL4728032 | 0.75 | GRM1 (0.57) | GRM1MEN1KMT2AALDH1A1P2RX7 | |
| SCHEMBL8215082 | 0.74 | HPGDS (0.42) | — | |
| SCHEMBL8212845 | 0.74 | ALDH1A1 (0.42) | PDGFRBPDGFRAGRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |