Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729605 | 0.86 | MAPK1 (0.41) | KMT2APOLBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4726333 | 0.86 | ALDH1A1 (0.38) | TDP2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4729677 | 0.85 | CYP1A1 (0.41) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4728618 | 0.84 | ALDH1A1 (0.48) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL4728950 | 0.82 | TDP2 (0.40) | TDP2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4726892 | 0.75 | TDP2 (0.46) | TDP2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4728001 | 0.72 | ALDH1A1 (0.41) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL22070762 | 0.72 | MEN1 (0.50) | TDP2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL31650113 | 0.71 | TDP2 (0.40) | TDP2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL10900104 | 0.71 | BCL2 (0.47) | TDP2KMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |