Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726333 | 0.85 | ALDH1A1 (0.38) | MAPTALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL4728954 | 0.85 | TDP2 (0.45) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL4729605 | 0.85 | MAPK1 (0.41) | TP53MAPTALDH1A1KDM4EUSP2 | |
| SCHEMBL4728618 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4727256 | 0.82 | CYP19A1 (0.50) | PPARGMTNR1ATP53MAPTCYP19A1 | |
| SCHEMBL17978220 | 0.79 | CYP19A1 (0.51) | MTNR1ATP53MAPTCYP19A1ALDH1A1 | |
| SCHEMBL4784489 | 0.76 | CYP1A1 (0.41) | CYP1A1PPARGBRD4MAPTATM | |
| SCHEMBL19128297 | 0.73 | CYP24A1 (0.51) | PPARGMAPTCYP19A1ALDH1A1KDM4E | |
| SCHEMBL24188767 | 0.72 | KDM4E (0.43) | PPARGBRD4MAPTALDH1A1KDM4E | |
| SCHEMBL12890 | 0.72 | L3MBTL1 (0.45) | PPARGBRD4MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |