Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729097 | 0.88 | ALDH1A1 (0.38) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL4728566 | 0.83 | RAB9A (0.64) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL5979923 | 0.72 | PPARG (0.37) | — | |
| SCHEMBL2706151 | 0.71 | RAB9A (0.65) | RAB9AL3MBTL1NPC1MEN1MAPT | |
| SCHEMBL27431499 | 0.70 | RAB9A (0.69) | RAB9AL3MBTL1NPC1MEN1MAPT | |
| SCHEMBL4729130 | 0.68 | RAB9A (0.45) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL10222540 | 0.68 | ALDH1A1 (0.58) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL201471 | 0.68 | MEN1 (0.65) | RAB9AL3MBTL1NPC1TDP1MEN1 | |
| SCHEMBL6822229 | 0.68 | RAB9A (0.67) | RAB9AL3MBTL1NPC1MEN1MAPT | |
| SCHEMBL4190948 | 0.68 | ALDH1A1 (0.67) | RAB9ANPC1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033455-A2 | BIPHENYL AND HETEROARYL PHENYL DERIVATIVES AS PROTEIN TYROSINE PHOSPHATASES INHIBITORS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2008-03-20 | — | — | WO | disclosed |