Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729129 | 0.83 | RAB9A (0.40) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL4729097 | 0.81 | ALDH1A1 (0.38) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL4784274 | 0.80 | RAB9A (0.76) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL4726570 | 0.78 | RAB9A (0.76) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL4727751 | 0.77 | RAB9A (0.74) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL4728570 | 0.74 | RAB9A (0.69) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL4728571 | 0.72 | L3MBTL1 (0.71) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL5522127 | 0.72 | RAB9A (0.67) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL4725515 | 0.71 | L3MBTL1 (0.55) | RAB9AL3MBTL1NPC1CASP3SENP8 | |
| SCHEMBL1927912 | 0.70 | MAPT (0.69) | RAB9AL3MBTL1NPC1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033455-A2 | BIPHENYL AND HETEROARYL PHENYL DERIVATIVES AS PROTEIN TYROSINE PHOSPHATASES INHIBITORS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2008-03-20 | — | — | WO | disclosed |