Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870690 | 0.75 | MGAM (0.48) | ALDH1A1GAAMAPTHDAC8HSD17B10 | |
| SCHEMBL7375731 | 0.74 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTKDM4CHDAC8 | |
| SCHEMBL10605297 | 0.73 | HDAC6 (0.52) | ALDH1A1GAAMAPTKDM4CHSD17B10 | |
| SCHEMBL29457163 | 0.71 | CYP1A2 (0.47) | ALDH1A1GAAMAPTHDAC8HSD17B10 | |
| SCHEMBL4725705 | 0.71 | HDAC1 (0.51) | ALDH1A1GAAMAPTKDM4CHDAC8 | |
| SCHEMBL7527822 | 0.70 | GRM7 (0.54) | ALDH1A1GAACYP1A2LMNAPKM | |
| SCHEMBL27721065 | 0.69 | MGAM (0.50) | ALDH1A1GAAMAPTKDM4CHDAC8 | |
| SCHEMBL5721000 | 0.69 | KDM4E (0.46) | ALDH1A1GAAMAPTKDM4CHDAC8 | |
| SCHEMBL5720996 | 0.69 | KDM4E (0.46) | ALDH1A1GAAMAPTKDM4CHDAC8 | |
| SCHEMBL29858224 | 0.69 | KDM4E (0.53) | ALDH1A1GAAMAPTHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |