SCHEMBL472917

SCHEMBL472917

O=c1ccn(O)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3291478 0.97
SCHEMBL9813341 0.65 DRD2 (0.34)
SCHEMBL4375225 0.64 CA12 (0.47)
SCHEMBL16402861 0.64
SCHEMBL666590 0.61
SCHEMBL9525683 0.61
SCHEMBL6448392 0.61
SCHEMBL6332988 0.61 KMT2A (0.34)
SCHEMBL7319404 0.59 KMT2A (0.52)
SCHEMBL722089 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300497-A Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria TOYAMA CHEMICAL CO., LTD. (JP) 1994-04-05 US claimed
US-5185330-A Penicillins/ad/ TOYAMA CHEMICAL CO., LTD. (JP) 1993-02-09 US claimed
CN-114832119-B Radioactive gel microsphere and preparation method and application thereof 苏州大学 2024-02-09 CN disclosed
CN-114832119-A Radioactive gel microsphere and preparation method and application thereof 苏州大学 2022-08-02 CN disclosed
CN-114716366-A 3-hydroxypyridine-4-ketone derivatives and application thereof in inhibition of renal cell iron death 浙江大学 2022-07-08 CN disclosed
US-10548860-B2 HIF-1 modulator paint formulation and uses thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2020-02-04 US disclosed
CN-106232656-B Michael acceptor-terminated urethane-containing fuel resistant prepolymers and compositions thereof PRC-迪索托国际公司 2019-11-26 CN disclosed
US-20190192452-A1 HIF-1 MODULATOR PAINT FORMULATION AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY 2019-06-27 US disclosed
CN-106232680-B Phosphine catalyst, sulfur-containing polymer composition that Michael's addition-is curable PRC-迪索托国际公司 2019-05-17 CN disclosed
US-10220009-B2 HIF-1 modulator paint formulation and uses thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2019-03-05 US disclosed
CN-105814117-B Metal ligand-containing prepolymers, methods of synthesis and compositions thereof PRC-迪索托国际公司 2019-02-12 CN disclosed
EP-0107458-B1 PHARMACEUTICAL COMPOSITIONS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1987-07-29 EP disclosed
US-4650793-A NITROGEN-SUBSTITUTED NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1987-03-17 US disclosed
EP-0094149-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING A COMPLEX OF IRON WITH N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR -4-ONE DERIVATIVES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-09-10 EP disclosed
US-4575502-A IRON DEFICIENCY ANEMIA NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-03-11 US disclosed
EP-0159917-A2 Pharmaceutical composition containing a hydroxypyrone-iron complex NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-10-30 EP disclosed
US-4550101-A Iron complexes of hydroxy pyridones useful for treating iron deficiency anemia NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-10-29 US disclosed
EP-0120670-A1 Iron III complexes of hydroxypyridones, and their pharmaceutical compositions NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-10-03 EP disclosed
EP-0107458-A1 Pharmaceutical compositions NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-05-02 EP disclosed
EP-0094149-A2 Pharmaceutical compositions containing a complex of iron with N-substituted 3-hydroxypyrid-2-one or -4-one derivatives NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1983-11-16 EP disclosed