Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632603 | 0.86 | ESR2 (0.35) | DRD2DRD4DRD3PKM | |
| SCHEMBL472917 | 0.65 | — | — | |
| SCHEMBL11547435 | 0.65 | NOTUM (0.38) | DRD2DRD4DRD3ALDH1A1POLB | |
| SCHEMBL27293556 | 0.64 | TOP2A (0.36) | ALDH1A1POLB | |
| SCHEMBL3291478 | 0.63 | — | — | |
| SCHEMBL26817236 | 0.61 | HSD11B1 (0.38) | — | |
| SCHEMBL6332988 | 0.59 | KMT2A (0.34) | — | |
| SCHEMBL1423865 | 0.59 | — | — | |
| SCHEMBL17233963 | 0.59 | — | — | |
| SCHEMBL9392147 | 0.59 | ALDH1A1 (0.30) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1017902-B | PROCESS FOR THE PREPARATION OF NOVEL CEPHALOSPORIN DERIVATIVES | MEIJI PHARMACEUTIAL LTD (JP) | 1992-08-19 | — | — | CN | disclosed |
| EP-0153709-B1 | NOVEL CEPHALOSPORIN DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4855420-A | Cephalosporin derivatives | ICI PHARMA (FR) | 1989-08-08 | — | — | US | disclosed |
| US-4785090-A | ANTIBIOTICS, BACTERICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1988-11-15 | — | — | US | disclosed |
| US-4678781-A | BACTERICIDAL ANTIBIOTICS | ICI PHARMA (FR) | 1987-07-07 | — | — | US | disclosed |
| CN-85105120-A | The preparation method of novel cephalosporin derivatives | — | 1986-12-31 | — | — | CN | disclosed |