Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517466 | 0.82 | IDO1 (0.72) | IDO1TDO2 | |
| SCHEMBL4728327 | 0.79 | IDO1 (0.53) | IDO1 | |
| SCHEMBL4729189 | 0.77 | RIPK1 (0.48) | TDO2 | |
| SCHEMBL4729197 | 0.77 | RIPK1 (0.48) | TDO2 | |
| SCHEMBL4368299 | 0.75 | IDO1 (0.66) | IDO1TDO2 | |
| SCHEMBL21372927 | 0.71 | IDO1 (0.47) | IDO1TDO2 | |
| SCHEMBL21372778 | 0.71 | IDO1 (0.47) | IDO1TDO2 | |
| SCHEMBL14214640 | 0.70 | RIPK1 (0.49) | TDO2 | |
| SCHEMBL20585354 | 0.69 | IDO1 (1.00) | IDO1 | |
| SCHEMBL21372751 | 0.69 | IDO1 (0.45) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080119491-A1 | AMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | INCYTE CORPORATION (US) | 2008-05-22 | — | — | US | claimed |
| WO-2008036643-A2 | AMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | INCYTE CORPORATION (US) | 2008-03-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119491-A1 | AMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | IDO1 1/4885TDO2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.