SCHEMBL4729281

SCHEMBL4729281

CC(C(=O)NO)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.63
HDAC4 P56524 1/20 0.63
HDAC1 Q13547 1/20 0.63
HDAC7 Q8WUI4 1/20 0.63
HDAC2 Q92769 1/20 0.63
HDAC10 Q969S8 1/20 0.63
HDAC11 Q96DB2 1/20 0.63
HDAC8 Q9BY41 1/20 0.63
HDAC6 Q9UBN7 1/20 0.63
HDAC9 Q9UKV0 1/20 0.63
HDAC5 Q9UQL6 1/20 0.63
CHRM1 P11229 1/20 0.59
PDE4A P27815 1/20 0.59
GRM7 Q14831 2/20 0.54
POLB P06746 1/20 0.54
MMP8 P22894 3/20 0.51
MMP9 P14780 3/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7559906 1.00 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Benzoic Acid SCHEMBL28031924 0.91 HDAC1 (0.53) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL3135701 0.83 LMNA (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2055558 0.83 LMNA (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL2055561 0.83 LMNA (0.55) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL6904220 0.82 GRM7 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL15522550 0.81 CHRM1 (0.62) HDAC1HDAC2HDAC8CHRM1PDE4A
SCHEMBL9848999 0.81 GRM7 (0.53) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL18885406 0.81 GPR88 (0.53) GRM7POLBMEN1KMT2ALMNA
SCHEMBL13712793 0.81 CHRM1 (0.62) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107648177-A A kind of profit repairs facial mask for releiving for sensitive skin 诺斯贝尔化妆品股份有限公司 2018-02-02 CN claimed
CN-107412097-A A kind of anti-acne repairs Essence 广州蜜妆生物科技有限公司 2017-12-01 CN claimed
CN-105078821-A Anti-irritating anti-allergic product containing fresh aloe juice and preparation method of anti-irritating anti-allergic product TAISHAN AGHG ALOE PRODUCTS CO LTD 2015-11-25 CN claimed
EP-1620087-A1 AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES, LTD. (IN) 2006-02-01 EP claimed
WO-2004089364-A1 AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2004-10-21 WO claimed
CN-110403896-A A kind of probiotics facial mask GUANGZHOU AIBEI BIOLOGICAL TECH CO LTD 2019-11-05 CN disclosed
CN-110200895-A A kind of cosmetic composition and the preparation method and application thereof containing plant component 广州柏俐臣化妆品有限公司 2019-09-06 CN disclosed
CN-109528576-A Antiallergic maintenance composition and its application 广州柚子舍生物科技有限公司 2019-03-29 CN disclosed
CN-109528576-A Antiallergic maintenance composition and its application 广州柚子舍生物科技有限公司 2019-03-29 CN disclosed
CN-109464373-A A kind of antiallergic facial treatment mask 上海悦目化妆品有限公司 2019-03-15 CN disclosed
CN-109431836-A One kind removing scar composition and preparation method thereof 广州博科健康科技集团有限公司 2019-03-08 CN disclosed
CN-107233223-B Control induction melanin target composition and its application 湖南御家化妆品制造有限公司 2019-01-25 CN disclosed
EP-0935669-B1 ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE HYDROXAMIC ACIDS AND THEIR CONVERSION INTO OPTICALLY ACTIVE PRIMARY AMINES BY LOSSEN TRANSPOSITION FRAUNHOFER GES FORSCHUNG (DE) 2002-07-31 EP disclosed
US-6281003-B1 REACTING RACEMIC AMIDE, CARBOXYLIC ACID OR ESTER WITH HYDROXYLAMINE FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) 2001-08-28 US disclosed
EP-0935669-A1 ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE HYDROXAMIC ACIDS AND THEIR CONVERSION INTO OPTICALLY ACTIVE PRIMARY AMINES BY LOSSEN TRANSPOSITION FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1999-08-18 EP disclosed
WO-1997044480-A1 ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE HYDROXAMIC ACIDS AND THEIR CONVERSION INTO OPTICALLY ACTIVE PRIMARY AMINES BY LOSSEN TRANSPOSITION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 1997-11-27 WO disclosed
EP-0273451-B1 LIPOXYGENASE INHIBITORY COMPOUNDS Bristol-Myers Squibb Company (US) 1992-04-01 EP disclosed
US-4861798-A Lipoxygenase inhibitory compounds BRISTOL-MYERS COMPANY (US) 1989-08-29 US disclosed
EP-0273451-A2 Lipoxygenase inhibitory compounds Bristol-Myers Squibb Company (US) 1988-07-06 EP disclosed
US-4731382-A Lipoxygenase inhibitory phenylalkanohydroxamic acids BRISTOL-MYERS COMPANY (US) 1988-03-15 US disclosed