Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729281 | 1.00 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Benzoic Acid SCHEMBL28031924 | 0.91 | HDAC1 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3135701 | 0.83 | LMNA (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2055558 | 0.83 | LMNA (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2055561 | 0.83 | LMNA (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6904220 | 0.82 | GRM7 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15522550 | 0.81 | CHRM1 (0.62) | HDAC1HDAC2HDAC8CHRM1PDE4A | |
| SCHEMBL9848999 | 0.81 | GRM7 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL18885406 | 0.81 | GPR88 (0.53) | GRM7POLBMEN1KMT2ALMNA | |
| SCHEMBL13712793 | 0.81 | CHRM1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935669-B1 | ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE HYDROXAMIC ACIDS AND THEIR CONVERSION INTO OPTICALLY ACTIVE PRIMARY AMINES BY LOSSEN TRANSPOSITION | FRAUNHOFER GES FORSCHUNG (DE) | 2002-07-31 | — | — | EP | disclosed |
| US-6350902-B2 | REACTING HYDROXYAMINE WITH A TRIFLUOROFORMATE ESTER | ABBOTT LABORATORIES | 2002-02-26 | — | — | US | disclosed |
| US-20020002307-A1 | Process for the selective N-formylation of N-hydroxylamines | ABBOTT LABORATORIES | 2002-01-03 | — | — | US | disclosed |
| US-20010031896-A1 | Process for the selective N-formylation of N-hydroxylamines | ABBOTT LABORATORIES | 2001-10-18 | — | — | US | disclosed |
| US-6281003-B1 | REACTING RACEMIC AMIDE, CARBOXYLIC ACID OR ESTER WITH HYDROXYLAMINE | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) | 2001-08-28 | — | — | US | disclosed |
| EP-0935669-A1 | ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE HYDROXAMIC ACIDS AND THEIR CONVERSION INTO OPTICALLY ACTIVE PRIMARY AMINES BY LOSSEN TRANSPOSITION | FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 1999-08-18 | — | — | EP | disclosed |
| WO-1997044480-A1 | ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE HYDROXAMIC ACIDS AND THEIR CONVERSION INTO OPTICALLY ACTIVE PRIMARY AMINES BY LOSSEN TRANSPOSITION | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 1997-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031896-A1 | Process for the selective N-formylation of N-hydroxylamines | HNMT, INMT, PNMT | HDAC3 2019/4885HDAC4 1233/4885HDAC1 3402/4885 |
| US-20020002307-A1 | Process for the selective N-formylation of N-hydroxylamines | HNMT, INMT, PNMT | HDAC3 2019/4885HDAC4 1233/4885HDAC1 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.