SCHEMBL4729330

SCHEMBL4729330

C#Cc1cccc2c3ccccc3c3ccccc3c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
THRB P10828 1/20 0.44
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
FABP7 O15540 1/20 0.33
FABP3 P05413 1/20 0.33
FABP5 Q01469 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
CYP2A6 P11509 2/20 0.32
CYP19A1 P11511 1/20 0.31
ERBB2 P04626 1/20 0.31
FYN P06241 1/20 0.31
MAOA P21397 1/20 0.31
ACHE P22303 1/20 0.31
AHR P35869 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28343137 0.84 ALDH1A1 (0.34) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL6894903 0.78 FABP7 (0.39) CYP1A2ALDH1A1HPGDHSD17B10CA1
SCHEMBL6129153 0.78 HSD17B10 (0.48) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL25056552 0.76 CDC14B (0.47) ALDH1A1HPGDHSD17B10MAOAAHR
SCHEMBL15797401 0.76 HSD17B10 (0.52) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL19409989 0.75 ALDH1A1 (0.44) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL29977314 0.75 CYP1A2 (0.48) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL21858100 0.75 ALDH1A1 (0.44) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL186670 0.75 CYP1A2 (0.48) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL29549980 0.75 CYP1A2 (0.48) CYP1A2ALDH1A1HPGDHSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008039529-A1 EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-04-03 WO disclosed