SCHEMBL28343137

SCHEMBL28343137

C#Cc1cccc2c1c1c3ccccc3c3c4ccccc4c4c5ccccc5c5c6ccccc6c6c7ccccc7c2c2c6c5c4c3c12

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
FABP7 O15540 1/20 0.31
FABP3 P05413 1/20 0.31
FABP5 Q01469 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4729330 0.84 CYP1A2 (0.44) ALDH1A1CYP1A2THRBHPGDHSD17B10
SCHEMBL1535077 0.75 ALDH1A1 (0.52) ALDH1A1CYP1A2THRBHPGDHSD17B10
SCHEMBL6894903 0.73 FABP7 (0.39) ALDH1A1CYP1A2HPGDHSD17B10FABP7
SCHEMBL1978995 0.72 CYP1A2 (0.58) ALDH1A1CYP1A2THRBHPGDHSD17B10
SCHEMBL5471145 0.72 CYP1A2 (0.58) ALDH1A1CYP1A2THRBHPGDHSD17B10
SCHEMBL5478700 0.72 CYP1A2 (0.58) ALDH1A1CYP1A2THRBHPGDHSD17B10
SCHEMBL5471214 0.72 CYP1A2 (0.58) ALDH1A1CYP1A2THRBHPGDHSD17B10
SCHEMBL11302617 0.72 CYP1A2 (0.58) ALDH1A1CYP1A2THRBHPGDHSD17B10
SCHEMBL6129153 0.72 HSD17B10 (0.48) ALDH1A1CYP1A2THRBHPGDHSD17B10
SCHEMBL25056552 0.71 CDC14B (0.47) ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110684050-B Preparation method and application of 7-position vinyl substituted osmium heteropentadiyne 厦门大学 2021-04-20 CN disclosed
CN-110684050-A Preparation method and application of 7-position vinyl substituted osmium heteropentadiyne 厦门大学 2020-01-14 CN disclosed