Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22516676 | 0.79 | TDP1 (0.52) | ALDH1A1HSD17B10TDP1PAX8LMNA | |
| SCHEMBL29956703 | 0.79 | TDP1 (0.52) | ALDH1A1HSD17B10TDP1PAX8LMNA | |
| SCHEMBL6187822 | 0.76 | PAX8 (0.47) | ALDH1A1HSD17B10TDP1PDGFRBPDGFRA | |
| SCHEMBL17519203 | 0.73 | PDGFRB (0.50) | ALDH1A1HSD17B10TDP1PDGFRBPDGFRA | |
| SCHEMBL4033357 | 0.73 | ALDH1A1 (0.69) | ALDH1A1HSD17B10TDP1PAX8LMNA | |
| SCHEMBL15941604 | 0.73 | PDGFRB (0.42) | ALDH1A1PDGFRBPDGFRALMNARAB9A | |
| SCHEMBL9989497 | 0.73 | PDGFRB (0.50) | ALDH1A1HSD17B10PDGFRBPDGFRAPAX8 | |
| SCHEMBL5477177 | 0.73 | PDGFRB (0.50) | ALDH1A1HSD17B10PDGFRBPDGFRAPAX8 | |
| SCHEMBL19465188 | 0.73 | CYP1A2 (0.47) | ALDH1A1HSD17B10PDGFRBPDGFRARAB9A | |
| SCHEMBL15865580 | 0.73 | PDGFRB (0.50) | ALDH1A1HSD17B10TDP1PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035049-A1 | ADAMANTANYL-(CYCLOPROPYL)-KETONES AS METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-03-27 | — | — | WO | disclosed |