SCHEMBL4729467 — predicted protein targets

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	RNASE1	P07998	1/20	0.42

▸	LMNA	P02545	2/20	0.41

▸	SMN1; SMN2	Q16637	2/20	0.41

▸	ALOX12	P18054	1/20	0.41

▸	ADRA1A	P35348	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15061820	0.91	RNASE1 (0.44)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL2611630	0.88	RNASE1 (0.42)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL2122164	0.88	RNASE1 (0.42)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL2122161	0.88	RNASE1 (0.42)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL20810870	0.87	RNASE1 (0.43)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL20810838	0.87	RNASE1 (0.43)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL2619370	0.87	RNASE1 (0.43)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL1566423	0.87	RNASE1 (0.48)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL7221864	0.87	RNASE1 (0.48)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A
SCHEMBL20974276	0.87	RNASE1 (0.41)	RNASE1LMNASMN1; SMN2ALOX12ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008037568-A2	REVERSIBLE TERMINATORS FOR EFFICIENT SEQUENCING BY SYNTHESIS	QUIATECH AB (SE)	2008-04-03	—	—	WO	disclosed