Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1566423 | 1.00 | RNASE1 (0.48) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL15061820 | 0.89 | RNASE1 (0.44) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL14397161 | 0.89 | RNASE1 (0.38) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL2619370 | 0.89 | RNASE1 (0.43) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL20810838 | 0.89 | RNASE1 (0.43) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL20810870 | 0.89 | RNASE1 (0.43) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL2611630 | 0.88 | RNASE1 (0.42) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL2122164 | 0.88 | RNASE1 (0.42) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL2122161 | 0.88 | RNASE1 (0.42) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A | |
| SCHEMBL4729467 | 0.87 | RNASE1 (0.42) | RNASE1LMNASMN1; SMN2ALOX12ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627456-B1 | Incorporating into the oligonucleotide analogs that are the components of a library to which in vitro selection methods functionalized standard and non-standard nucleotides, and incorporating functionalized cofactors into the experiment | BENNER, STEVEN | 2003-09-30 | — | — | US | disclosed |
| US-5965364-A | Method for selecting functional deoxyribonucleotide derivatives | BENNER, STEVEN | 1999-10-12 | — | — | US | disclosed |