Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | PGK1 | P00558 | 8/20 | 0.48 |
| ▸ | PGK2 | P07205 | 8/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262029 | 0.83 | CA2 (0.65) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL12353499 | 0.76 | GRIK1 (0.62) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL4954253 | 0.74 | CA2 (0.54) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL3355826 | 0.73 | CA2 (0.52) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL31467547 | 0.73 | PGK1 (0.53) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL4126405 | 0.73 | PGK1 (0.53) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL916920 | 0.73 | PGK1 (0.53) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL342414 | 0.73 | CA2 (0.52) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL14097219 | 0.73 | CA2 (0.52) | CA2CA4CA5APGK1PGK2 | |
| SCHEMBL30586458 | 0.73 | PGK1 (0.53) | CA2CA4CA5APGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | claimed |
| WO-2008031888-A2 | CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS | CAMPIANI GIUSEPPE (IT) | 2008-03-20 | — | — | WO | disclosed |