Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801532 | 0.84 | ALOX5 (0.55) | ALOX5MAPTTP53POLBHDAC1 | |
| SCHEMBL28009432 | 0.84 | ALOX5 (0.55) | ALOX5MAPTTP53POLB | |
| SCHEMBL25239501 | 0.79 | ALOX5 (0.62) | ALOX5MAPTTP53POLB | |
| SCHEMBL21393181 | 0.77 | MAPK1 (0.66) | ALOX5MAPTTP53POLB | |
| SCHEMBL27867316 | 0.75 | ALOX5 (0.56) | ALOX5MAPTTP53POLB | |
| SCHEMBL19712891 | 0.75 | GAA (0.43) | ALOX5MAPTPOLB | |
| SCHEMBL2834886 | 0.75 | ALOX5 (0.56) | ALOX5MAPTTP53POLBHDAC1 | |
| SCHEMBL8808956 | 0.74 | ALOX5 (1.00) | ALOX5MAPTTP53 | |
| SCHEMBL6824498 | 0.73 | ALOX5 (0.58) | ALOX5MAPTTP53POLB | |
| SCHEMBL28226212 | 0.73 | TRPM8 (0.67) | ALOX5MAPTTP53POLBTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008088126-A | FURYLMETHYLENE MALONAMIDE COMPOUND AND SALT THEREOF, ULTRAVIOLET LIGHT ABSORBER AND EXTERNAL PREPARATION FOR SKIN | SHISEIDO CO LTD | 2008-04-17 | — | — | JP | disclosed |
| WO-2008041525-A1 | FURYLMETHYLENE MALONAMIDE COMPOUND AND SALT THEREOF, ULTRAVIOLET RAY ABSORBENT, AND EXTERNAL PREPARATION FOR SKIN | SHISEIDO COMPANY LTD. (JP) | 2008-04-10 | — | — | WO | disclosed |