Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729618 | 0.84 | ALOX5 (0.58) | ALOX5MAPTTP53POLBHDAC1 | |
| SCHEMBL25239501 | 0.77 | ALOX5 (0.62) | ALOX5MAPTTP53ALDH1A1TSHR | |
| SCHEMBL2100645 | 0.76 | ALOX5 (0.51) | ALOX5MAPTALDH1A1POLBHDAC1 | |
| SCHEMBL11234382 | 0.75 | ALDH1A1 (0.50) | ALOX5MAPTALDH1A1POLB | |
| SCHEMBL21393181 | 0.74 | MAPK1 (0.66) | ALOX5MAPTTP53ALDH1A1TSHR | |
| SCHEMBL1326250 | 0.74 | ALOX5 (0.53) | ALOX5MAPTALDH1A1POLBHDAC1 | |
| SCHEMBL17801568 | 0.74 | ALOX5 (0.56) | ALOX5MAPTTP53ALDH1A1TSHR | |
| SCHEMBL3217675 | 0.73 | ALDH1A1 (0.53) | ALOX5MAPTALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL5352595 | 0.73 | ALOX5 (0.51) | ALOX5MAPTALDH1A1POLBHDAC1 | |
| SCHEMBL27867316 | 0.73 | ALOX5 (0.56) | ALOX5MAPTTP53ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200108146-A1 | Nucleophile-Triggered Degradable Materials and Methods of Making and Using the Same | NATIONAL SCIENCE FOUNDATION | 2020-04-09 | — | — | US | disclosed |
| US-20170360940-A1 | NUCLEOPHILE-TRIGGERED DEGRADABLE MATERIALS AND METHODS OF MAKING AND USING THE SAME | NATIONAL SCIENCE FOUNDATION | 2017-12-21 | — | — | US | disclosed |
| WO-2016090060-A1 | NUCLEOPHILE-TRIGGERED DEGRADBLE MATERIALS AND METHODS OF MAKING AND USING THE SAME | GEORGIA TECH RESEARCH CORPORATION (US) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360940-A1 | NUCLEOPHILE-TRIGGERED DEGRADABLE MATERIALS AND METHODS OF MAKING AND USING THE SAME | OGG1, MRE11, DNA2 | ALOX5 1036/4885MAPT 4138/4885TP53 3342/4885 |
| US-20200108146-A1 | Nucleophile-Triggered Degradable Materials and Methods of Making and Using the Same | MRE11, ENDOD1, DNASE1 | ALOX5 1214/4885MAPT 4136/4885TP53 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.