Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.53 |
| ▸ | HTR2A | P28223 | 18/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.53 |
| ▸ | HTR1A | P08908 | 17/20 | 0.53 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729856 | 0.96 | DRD2 (0.56) | DRD2HTR2ASLC6A4HTR1ADAPK3 | |
| SCHEMBL4780926 | 0.77 | CLK4 (0.47) | DRD2HTR2ASLC6A4HTR1ADAPK3 | |
| SCHEMBL1079809 | 0.74 | CLK4 (0.51) | DRD2HTR2ASLC6A4HTR1ADAPK3 | |
| SCHEMBL4728027 | 0.74 | DRD2 (0.52) | DRD2HTR2ASLC6A4HTR1ANTRK1 | |
| SCHEMBL4728129 | 0.74 | GRM5 (0.42) | DRD2HTR2ASLC6A4HTR1ADAPK3 | |
| SCHEMBL4726294 | 0.71 | DRD2 (0.54) | DRD2HTR2ASLC6A4HTR1A | |
| SCHEMBL13827240 | 0.71 | CLK4 (0.47) | DRD2HTR2ASLC6A4HTR1ADAPK3 | |
| SCHEMBL4725780 | 0.71 | DRD2 (1.00) | DRD2HTR2ASLC6A4HTR1A | |
| SCHEMBL4729111 | 0.71 | DRD2 (1.00) | DRD2HTR2ASLC6A4HTR1A | |
| SCHEMBL4728964 | 0.70 | DRD2 (1.00) | DRD2HTR2ASLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | disclosed |