Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865177 | 0.89 | L3MBTL1 (0.54) | L3MBTL1AKR1C3GAAMAPTALDH1A1 | |
| SCHEMBL4622029 | 0.81 | L3MBTL1 (0.50) | L3MBTL1AKR1C3GAAMAPTALDH1A1 | |
| SCHEMBL857849 | 0.80 | AKR1C3 (0.67) | L3MBTL1AKR1C3GAAMAPTMYC | |
| SCHEMBL14062333 | 0.79 | FOLH1 (0.60) | L3MBTL1AKR1C3GAAMAPTMYC | |
| SCHEMBL9358998 | 0.79 | L3MBTL1 (0.52) | L3MBTL1AKR1C3GAAMAPTALDH1A1 | |
| SCHEMBL9774810 | 0.78 | AKR1C3 (0.64) | L3MBTL1AKR1C3GAAMAPTMYC | |
| SCHEMBL14688521 | 0.77 | AKR1C3 (0.58) | L3MBTL1AKR1C3GAAMAPTMYC | |
| SCHEMBL11036287 | 0.77 | AKR1C3 (0.61) | L3MBTL1AKR1C3GAAMAPTALDH1A1 | |
| SCHEMBL1667162 | 0.77 | AKR1C3 (0.61) | L3MBTL1AKR1C3GAAMAPTMYC | |
| SCHEMBL24834273 | 0.76 | CYP3A4 (0.46) | L3MBTL1AKR1C3GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080213334-A1 | Mixture of cationic polymer, anionic polymer and drug, that forms blended coatings and/or hydrogel coatings for controlled release of said drug from medical devices coated with or containing such media | Surmodics Coatings, LLC | 2008-09-04 | — | — | US | disclosed |
| WO-2008042748-A2 | POLYELECTROLYTE MEDIA FOR BIOACTIVE AGENT DELIVERY | SURMODICS, INC. (US) | 2008-04-10 | — | — | WO | disclosed |