Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729947 | 0.93 | ADRA1D (0.45) | ADRA1DADRA1A | |
| SCHEMBL4730966 | 0.93 | ADRA1D (0.47) | ADRA1DADRA1A | |
| SCHEMBL4731810 | 0.92 | ADRA1D (0.45) | ADRA1DADRA1A | |
| SCHEMBL4733170 | 0.92 | ADRA1D (0.45) | ADRA1DADRA1A | |
| SCHEMBL4727421 | 0.91 | ADRA1D (0.45) | ADRA1DADRA1A | |
| SCHEMBL4727388 | 0.86 | ADRA1D (0.42) | ADRA1DADRA1A | |
| SCHEMBL4731954 | 0.82 | ADRA1D (0.41) | ADRA1DADRA1A | |
| SCHEMBL4730949 | 0.80 | ADRA1D (0.56) | ADRA1DADRA1A | |
| SCHEMBL14066209 | 0.80 | ADRA1D (0.56) | ADRA1DADRA1A | |
| SCHEMBL14066207 | 0.79 | ADRA1A (0.53) | ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033513-A1 | ISOXAZOLINE ALPHA 1a/1d ADRENORECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-20 | — | — | WO | claimed |