SCHEMBL4729980

SCHEMBL4729980

[CH2]c1ccc(P(=O)(O)O)s1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA5A P35218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4729982 0.71 DAO (0.41) CA2CA4CA5A
SCHEMBL21101659 0.71 DAO (0.41) CA2CA4CA5A
SCHEMBL21102326 0.66 DAO (0.36)
SCHEMBL21101858 0.64 FDPS (0.43)
SCHEMBL4730423 0.60 CA2 (0.31) CA2CA4CA5A
SCHEMBL3247756 0.57 CA2 (0.55) CA2CA4CA5A
SCHEMBL2171752 0.55 CA2 (0.71) CA2CA4CA5A
Phosphoric Acid SCHEMBL27964422 0.51
Phosphoric Acid SCHEMBL448361 0.50 ACP3 (0.46) CA2CA4CA5A
Phosphoric Acid SCHEMBL76242 0.49

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008031888-A2 CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS CAMPIANI GIUSEPPE (IT) 2008-03-20 WO claimed
WO-2008031888-A2 CONDENSED PYRIMIDINONES ACTIVE ON GLUTAMATERGIC RECEPTORS CAMPIANI GIUSEPPE (IT) 2008-03-20 WO disclosed