Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 16/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | WNT3 | P56703 | 1/20 | 0.37 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730237 | 0.91 | MEN1 (0.39) | CCR8CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL4784267 | 0.90 | SFRP1 (0.48) | CCR8WNT3SFRP1 | |
| SCHEMBL4733197 | 0.88 | CCR8 (0.43) | CCR8MEN1KMT2A | |
| SCHEMBL4730986 | 0.88 | SFRP1 (0.46) | CCR8CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL4735363 | 0.88 | CCR8 (0.39) | CCR8MEN1KMT2ASFRP1 | |
| SCHEMBL4733261 | 0.85 | SFRP1 (0.51) | MEN1KMT2ASFRP1 | |
| SCHEMBL4731311 | 0.81 | SFRP1 (0.48) | CCR8WNT3SFRP1 | |
| SCHEMBL4733321 | 0.80 | CCR8 (0.47) | CCR8CYP3A4CYP2C19WNT3SFRP1 | |
| SCHEMBL4732159 | 0.80 | SFRP1 (0.49) | CCR8SFRP1 | |
| SCHEMBL4733195 | 0.79 | CCR8 (0.41) | CCR8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |