Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 17/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733195 | 0.91 | CCR8 (0.41) | CCR8KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL4732877 | 0.90 | SFRP1 (0.45) | CCR8MEN1KMT2A | |
| SCHEMBL4730240 | 0.88 | CCR8 (0.39) | CCR8MEN1KMT2A | |
| SCHEMBL4735363 | 0.86 | CCR8 (0.39) | CCR8MEN1KMT2A | |
| SCHEMBL4730495 | 0.84 | SFRP1 (0.50) | MEN1KMT2A | |
| SCHEMBL4730139 | 0.81 | SFRP1 (0.45) | CCR8MEN1KMT2A | |
| SCHEMBL4784267 | 0.80 | SFRP1 (0.48) | CCR8 | |
| SCHEMBL4730237 | 0.79 | MEN1 (0.39) | CCR8MEN1KMT2A | |
| SCHEMBL4730986 | 0.79 | SFRP1 (0.46) | CCR8MEN1KMT2A | |
| SCHEMBL4734862 | 0.78 | MEN1 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061029-A1 | ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |